| Tuesday, November 18, 2008 |
| Away Team | Home Team | Time |
42 Northern Illinois 
| 14 Kent State
| 7:00pm |
| Wednesday, November 19, 2008 |
| Away Team | Home Team | Time |
31 #14 Ball State
| 24 Central Michigan
| 7:00pm |
| Thursday, November 20, 2008 |
| Away Team | Home Team | Time |
23 #23 Miami (FL)
| 41 Georgia Tech
| 7:30pm |
| Friday, November 21, 2008 |
| Away Team | Home Team | Time |
| Buffalo
| Bowling Green
| 6:00pm |
| Miami (OH)
| Toledo
| 7:00pm |
| Fresno State
| San Jose State
| 9:30pm |
| Saturday, November 22, 2008 |
| Away Team | Home Team | Time |
| Indiana
| Purdue
| 12:00pm |
| Clemson
| Virginia
| 12:00pm |
| Army
| Rutgers
| 12:00pm |
| North Carolina State
| #25 North Carolina
| 12:00pm |
| West Virginia
| Louisville
| 12:00pm |
| Michigan
| #10 Ohio State
| 12:00pm |
| Tennessee
| Vanderbilt
| 12:30pm |
| Eastern Michigan
| Temple
| 1:00pm |
| Citadel | #3 Florida
| 1:30pm |
| Colorado State
| Wyoming
| 2:00pm |
| UCF
| Memphis
| 2:00pm |
| Arkansas
| Mississippi State
| 2:30pm |
| Syracuse
| Notre Dame
| 2:30pm |
| Washington
| Washington State
| 3:00pm |
| Tulane
| Tulsa
| 3:00pm |
| Florida Atlantic
| Arkansas State
| 3:00pm |
| UTEP
| Houston
| 3:30pm |
| North Texas
| Middle Tennessee State
| 3:30pm |
| Marshall
| Rice
| 3:30pm |
| Illinois
| Northwestern
| 3:30pm |
| Stanford
| California
| 3:30pm |
| Air Force
| #15 TCU
| 3:30pm |
| Iowa State
| Kansas State
| 3:30pm |
| Mississippi
| #18 LSU
| 3:30pm |
| Boston College
| Wake Forest
| 3:30pm |
| Cal Poly | Wisconsin
| 3:30pm |
| Akron
| Ohio
| 3:30pm |
| #17 Michigan State
| #7 Penn State
| 3:30pm |
| Louisiana Tech
| New Mexico State
| 4:00pm |
| #9 Boise State
| Nevada
| 4:05pm |
| Duke
| Virginia Tech
| 5:30pm |
| #16 BYU
| #8 Utah
| 6:00pm |
| East Carolina
| UAB
| 7:00pm |
| Louisiana-Lafayette
| Troy
| 7:00pm |
| Louisiana-Monroe
| Florida International
| 7:00pm |
| Iowa
| Minnesota
| 7:00pm |
| #20 Pittsburgh
| #19 Cincinnati
| 7:00pm |
| #21 Oregon State
| Arizona
| 7:00pm |
| Florida State
| #22 Maryland
| 7:45pm |
| #2 Texas Tech
| #5 Oklahoma
| 8:00pm |
| UNLV
| San Diego State
| 8:00pm |
| Idaho
| Hawaii
| 11:05pm |
| Sunday, November 23, 2008 |
| Away Team | Home Team | Time |
| Connecticut
| South Florida
| 8:00pm |